Checks and balances. Wyoming has 1 representative in the house, California has 53. When you combine the house and the senate, it should (in theory) be much harder for a bill to pass without approval of both the majority of the states and the majority of the population.

Theory is nothing without evidence, and in lived experience, not only do bills completely fail to pass due to overuse of the Senate filibuster, but the House itself is now so thoroughly gerrymandered as to not even represent the majority of the population -- since most House elections are not, statistically speaking, contested at all.